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Dr. Sanjay Kumar Principal Scientist Veterinary Medicine Kumarsanjay66@yahoo.com
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Area of Research Interests: Theileria equi is one of the highly endemic disease of equids in the country. We have developed recombinant antigen based ELISA for diagnosis. In host-parasite interaction rhoptry protein plays a major role. These proteins are thought to participate in host-cell recognition and thereby enhances invasion of the parasite into the host red blood cell. Information on the rhoptry protein of B. equi is still lacking and is another priority area of research for development of a suitable vaccine. We are also interested to identify a drug target in this organism and design drug molecule by using bioinformatic tools.
Biography:
Research Projects: OIE Twinning Project on Equine Piroplasmosis funded by World Animal Health Organization (OIE, Paris, France). This project is between National Research Centre for Protozoan Diseases, Obihiro Japan and National Research Centre on Equines, Hisar, India.
Selected Publications of the last five years:
1.
Kumar S,
Kumar R, Sugimoto C. 2009. A perspective on Theileria equi
infections in donkeys. Japanese Journal of
Veterinary Research, 56(4):171-80.
2. S.
Kumar,
R.
Kumar,
A.K. Gupta
and
S. K. Dwivedi.
2008. Passive
transfer
of
Theileria
equi
antibodies
to
neonate
foals
of
immune
tolerant
mares.
Veterinary
Parasitology,
151(1): 80-85.
3. Sanjeev
Kumar,
D.V.
Malhotra,
A.K.
Sangwan,
P.
Goel,
Ashok Kumar
and
S.
Kumar.
2007. Infectivity
rate
and
transmission
potential
of
Hyalomma
anatolicum
anatolicum
ticks
for
Babesia
equi
infection.
Veterinary
Parasitology,
144
(338-343).
4. Kumar,
S.
and
Kumar,
R.
2007. Diagnosis
of
Babesia
equi
infection:
An
update
on
the
methods
available.
CAB
Review:
Perspectives
in
Agriculture,
Veterinary
Sciences,
Nutrition
and
Natural
resources.
2 no.
(35)
1-14.
5. Bork
S,
Okamura
M,
Matsuo
T,
Kumar
S,
Yokoyama
N,
Igarashi
I.
2005.
Host serum
modifies
the
drug
susceptibility
of Babesia
bovis
in
vitro.
Parasitology.
130(Pt
5):489-92.
6. Kumar,
S.,
Kim
J.-Y.,
Yokoyama
N.,
Inoue N.,
Xuan X.,
Igarashi
I.,
Sugimoto
C..
2004. Expression
of Babesia
equi
EMA-1
and
EMA-2
during
merozoite
developmental
stages
in
erythrocyte
and
their
interaction
with
erythrocytic
membrane
skeleton.
Molecular
and Biochemical
Parasitology.
133: 221-227. 7. Bork, S., Yokoyama, N., Ikehara, Y., Kumar, S., Sugimoto, C and Igarashi, I. 2004. Growth inhibitory effect of heparin on Babesia equi parasites. Antimicrobial Agents and Chemotherapy. 48(1):236-241.
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